Includes bibliographical references and index.
|Statement||Susan D. Brain, Philip K. Moore, editors.|
|Series||Progress in inflammation research, PIR (Series)|
|Contributions||Brain, Susan D., 1955-, Moore, P. K. 1954-|
|LC Classifications||RB127 .P332153 1999|
|The Physical Object|
|Pagination||xii, 344 p. :|
|Number of Pages||344|
|ISBN 10||0817658750, 0817658750|
|LC Control Number||98054474|
From the Back Cover. Unprecedented progress in our understanding of the molecular biology, pharmacology, and pathophysiology of neurogenic inflammation has been made. Taking all advances together, it was felt that a comprehensive and up-to-date volume was badly needed, and the present book was designed to cover all the major contemporary aspects 5/5(1). Neuropeptides and the gut: Tachykinins and calcitonin gene-related peptide in intestinal inflammation and pain. Pain and Neurogenic Inflammation. by. Progress in Inflammation Research. Share your thoughts Complete your review. Tell readers what you thought by rating and reviewing this book. Rate it * You Rated it *Brand: Birkhäuser Basel. This book provides an integrated account of recent advances in the fields of pain and neurogenic inflammation. The volume is intended to bring together studies from eminent researchers in the often separate research fields of pain and inflammation.
Pain and Neurogenic Inflammation by P. K. Moore, , available at Book Depository with free delivery worldwide. PAIN AND NEUROGENIC INFLAMMATION. Search for other works by this author on: Published: When the neurochemist lifted the lid on nociceptors in the s, out of the Pandora's box flew a host of active substances, which at first produced astonishment, and then : P. Anand. The objective is to introduce and discuss the principle of neurogenic inflammation as a promising and innovative target field in pain medicine. The presented up-to-date data will provide an in-depth overview of neurotrophins and neuron-derived molecules in chronic pain syndromes such as osteoarthritis, migraine or low back pain. Neurogenic inflammation is a form of inflammation (redness, heat, swelling, pain) initiated by activation of peripheral nervous system c-fiber neurons rather than by immunological events. 98 The neuronal activity leads to neuropeptide release and inflammation at sites different from the original stimulus. Substance P is one of several peptides that mediate this process.
Typically, pain is due to an injury or illness. For example, if you drop a heavy book on your foot, your nervous system sends signals of pain immediately after the book hits. With neuropathic pain, no event or injury causes the pain. Instead, the body just sends pain signals to your brain : Kimberly Holland. Aims to bring together advances in the often separate fields of pain and neurogenic inflammation. This work focuses on important discoveries such as the cloning of the capsaicin receptor and the discovery of RAMP proteins for CGRP receptors. Spinal Cord Injury and Neuropathic Pain. Spinal cord injury (SCI) often results in devastating motor and sensory deficits for which current therapy is largely ineffective. Additionally, SCI can induce the development of chronic neuropathic pain states and significantly worsen the Cited by: Neurogenic inflammation and pain. Neurogenic inflammation results from nociceptor activation and can be experimentally caused with immediate onset by intradermal administration of capsaicin, which activates TRPV1, or mustard oil, which activates TRPA1 The activated nociceptors, notably C-fibers, release a host of neuropeptides such as substance P, CGRP, and by: